Irondale is a city in Jefferson County, Alabama, United States.It is a suburb of Birmingham, northeast of Homewood and Mountain Brook.At the 2020 census, the population was 13,497.. Irondale is the location of the Irondale Cafe. Author Fannie Flagg used this for her fictional setting in her novel Fried Green Tomatoes at the Whistle Stop Cafe (1987). The city is the site of …