This is a list of the National Register of Historic Places listings in Lake County, Indiana.. This is intended to be a complete list of the properties and districts on the National Register of Historic Places in Lake County, Indiana, United States.Latitude and longitude coordinates are provided for many National Register properties and districts; these locations may be seen together in a map.

Initially, the site of modern Lake Station was the starting point of two Amerind trails leading to Fort Dearborn. Later it became an early stagecoach depot stop, as the Fort Dearborn-Detroit Stagecoach Route passed through the site during the wet season. The location became known as Lake Station as far back as 1851 when it began to serve as a depot, the western terminus of …