2021年7月24日 · Serum therapy involves the administration of purified blood serum from immunized humans or animals (e.g., horses), which contains antibodies, as a form of passive immunization against many diseases and envenomation events. Serum therapy was first introduced in 1890, when Kitasato and von Behring discovered that serum derived from rabbits …

Emil von Behring is the father of serum therapy. We present an overview of the development of this important tool in the treatment of diphtheria. In a historical context Behring's work reflects the scientific spirit of fin de siècle Berlin.

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Serum therapy. Bull N Y Acad Med 1931;7:401-11. ※2 von Behring E, Kitasato S. Ueber das Zustandekommender Diphtherie-Immunität und der Tetanus-Immunitätbei Thieren. Deutsche Medicininischen ochenschrift1890;49:1113-4.

In contrast, autologous serum therapy significantly decreased IgE-anti-IL-24 serum levels, but not IgG-anti-IL-24 serum levels, in responders but not in non-responders. Conclusions: Our findings suggest that the immunological effects of autologous serum therapy include a reduction in IgE-anti-IL24 autoantibodies, which may contribute to the pathogenesis of CSU.

Serum free light-chain measurement. Immunoglobulin light chains that are circulating in serum in a free (unbound) state are called free light chains ( FLCs ). Measurement of the serum level of FLCs became practical as a clinical blood test in recent decades. These tests are used as an aid in the diagnosis and monitoring of multiple myeloma and ...

Le sérum est le liquide sanguin débarrassé de ses cellules et des protéines de la coagulation. C'est le liquide surnageant obtenu après coagulation et centrifugation du sang dans un tube « sec », c'est-à-dire sans inhibiteur de la coagulation. À l'inverse du plasma, qui lui est obtenu par simple centrifugation sans coagulation ...