pancreatic cancer portal vein involvement - EAS

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  1. Portal vein resection potentially provides the chance of margin-negative resection, and thus might be of benefit in selected patients with pancreatic cancer with portal vein involvement. However, it is unclear whether histological invasion of the portal vein is a prognostic factor influencing survival.
    Author: Toshio Nakagohri, Taira Kinoshita, Masaru Konishi, Kazuto Inoue, Shinichiro Takahashi
    Publish Year: 2003
    www.sciencedirect.com/science/article/pii/S0002961003001739
    www.sciencedirect.com/science/article/pii/S0002961003001739
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    What makes a pancreatic cancer resectable?
    Resectable pancreatic cancer If a tumor is “resectable,” it simply means that it is able to be removed with surgery. A physician may determine that pancreatic cancer is resectable if it is contained within the pancreas or surrounding area and not extending intro nearby blood vessels.
    www.pancreaticcancer.org.uk/information/just-diagnose…
    Who typically gets pancreatic cancer?

    Studies have found the following risk factors:

    • Age: The likelihood of developing pancreatic cancer increases with age. ...
    • Smoking: Cigarette smokers are two or three times more likely than nonsmokers to develop pancreatic cancer.
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    • Being male: More men than women are diagnosed with pancreatic cancer.

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    www.onhealth.com/content/1/pancreatic_cancer_risk_an…
    What to know about inoperable pancreatic cancer?
    Inoperable pancreatic cancer means doctors can’t remove the cancer surgically. Learn about different types (such as metastatic cancer), how they're treated, and more.
    www.webmd.com/cancer/inoperable-pancreatic-cancer
    Is pancreas cancer a contagious disease?
    No one knows the exact causes of pancreatic cancer. Doctors can seldom explain why one person gets pancreatic cancer and another does not. However, it is clear that this disease is not contagious. No one can "catch" cancer from another person.
    www.verywellhealth.com/is-cancer-contagious-514238
  3. https://pubmed.ncbi.nlm.nih.gov/9408502

    However, only 15% to 20% of patients are candidates for resection because of the presence of distant tumor outside the confines of resection or because of locally advanced disease. Even though isolated portal vein involvement has classically been a contraindication for resection,

    • Author: L E Harrison, M F Brennan
    • Publish Year: 1997
  4. https://pubmed.ncbi.nlm.nih.gov/28685356

    Abstract. Background: It remains controversial whether the degree of venous involvement really is associated with borderline resectability of pancreatic cancer. Methods: A single-center …

    • Author: Katsuhisa Ohgi, Yusuke Yamamoto, Teiichi Sugiura, Yukiyasu Okamura, Takaaki Ito, Ryo Ashida, Takeshi...
    • Publish Year: 2017
  5. https://pubmed.ncbi.nlm.nih.gov/27554501

    Impact of Portal Vein Involvement from Pancreatic Cancer on Metastatic Pattern After Surgical Resection. True invasion of the PV/SMV is an independent risk factor for overall survival, and …

    • Author: Franz Mierke, Sebastian Hempel, Marius Distler, Daniela E. Aust, Hans-Detlev Saeger, Jürgen Weitz, T...
    • Publish Year: 2016
  6. https://pubmed.ncbi.nlm.nih.gov/11677992

    Methodology: Fifteen patients with pancreatic head tumors and portal vein involvement were submitted to pancreaticoduodenectomy according to this technique. The main feature of the …

  7. https://pubmed.ncbi.nlm.nih.gov/16201124

    Methodology: This is a retrospective study of 48 patients who underwent portal vein/superior mesenteric vein (PV/SMV) resection along with PD using the modified technique of resection, …

  8. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3870522

    Dec 12, 2013 · Due to the close relationship between the pancreas and the superior mesenteric vein (SMV) and portal vein (PV), pancreatic cancer can infiltrate the PV/SMV. Research …

  9. Defining venous involvement in borderline resectable pancreatic cancer

    https://pubmed.ncbi.nlm.nih.gov/20725860

    Abstract. Background: Pancreatic adenocarcinoma impinging the portal and/or superior mesenteric vein (PV-SMV) is classified as borderline resectable, and preoperative chemoradiation is recommended to increase the margin-negative resection rate. There is no consensus about what degree of venous impingement constitutes borderline resectability.

  10. https://pancreaticcanceraction.org/about...

    Oct 15, 2019 · Portal vein resection is performed when the vein is involved and the surgeon believes they can remove all of the cancer. This is usually when the vein involvement is small and the surgeon thinks the operation will benefit the …

  11. https://pancreatica.org/pancreatic-cancer/pancreatic-cancer-stages

    In this proposed classification, potentially “resectable pancreatic cancer” stage (or Local) is defined roughly as that including no evidence of extra-pancreatic involvement of the tumor,

  12. https://pubmed.ncbi.nlm.nih.gov/8781933

    The clean resection rate was 86% when all tests were used, 78% if EUS was used without angiography, and 60% if only angiography was used. Conclusion: EUS is highly sensitive for …

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