hox family - EAS

About 19,900,000 results
  1. Homeobox
    • According to 3 sources
    The homeobox (HOX) genes are a highly conserved family of homeodomain-containing transcription factors that specify cell identity in early development and, subsequently, in a number of adult processes including hematopoiesis.
    Background: The homeobox (HOX) family consists of 39 genes whose expressions are tightly controlled and coordinated within the family, during development. We performed a comprehensive analysis of this gene family in cancer settings.
    Abstract Background The homeobox (HOX) gene family has been found to be involved in human cancers. However, its involvement in hepatocellular carcinoma (HCC) has not been well documented.
  2. People also ask
    What is the Hox family of genes?The HOX family genes, also known as type I homeobox genes, contain a conserved sequence consisting of 180–183 base pairs which encodes a homologous domain consisting of 60 or 61 amino acids. The homeodomain recognizes DNA sequences containing 5′-TAAT-3′ and regulates the transcriptional activity of downstream genes.
    www.sciencedirect.com/science/article/pii/S0898656819…
    Are hox family members tumor promoters or suppressors?As tumor promoters or suppressors HOX family members have been reported to be closely related with a variety of cancers. They closely regulate tumor initiation and growth, invasion and metastasis, angiogenesis, anti-cancer drug resistance and stem cell origin.
    www.sciencedirect.com/science/article/pii/S0898656819…
    What are the Hox genes in Caenorhabditis elegans?The nematode Caenorhabditis elegans (C. elegans) contains six Hox genes, abnormal cell lineage 39 (lin-39), male abnormal 5 (mab-5), homeobox 13 (ceh-13), egg-laying defective 5 (egl-5), posterior Hox gene paralogue 3 (php-3), and knob-like posterior (nob-1) (Burglin & Ruvkun, 1993; Wang et al., 1993).
    www.sciencedirect.com/topics/neuroscience/hox-gene
    Where are Hox genes located in the developing embryo?This means that Hox genes active anteriorly in the developing embryo are located normally at the 3′ end of the Hox cluster, while those expressed posteriorly are found at 5′ end of the same genomic region, a phenomenon known as spatial colinearity ( Gaunt, 1988; Graham et al., 1989; Kmita & Duboule, 2003 ).
    www.sciencedirect.com/topics/neuroscience/hox-gene
  3. https://pubmed.ncbi.nlm.nih.gov/31733300

    As tumor promoters or suppressors HOX family members have been reported to be closely related with a variety of cancers. They closely regulate tumor initiation and growth, invasion …

    • Author: Miao Yu, Jun Zhan, Hongquan Zhang
    • Publish Year: 2020
  4. https://pubmed.ncbi.nlm.nih.gov/2574852

    Dec 25, 1989 · We report the identification of 10 new human homeobox sequences. Altogether, we have isolated and sequenced 30 human homeoboxes clustered in 4 chromosomal regions …

  5. https://www.sciencedirect.com/science/article/pii/S0898656819302657

    Feb 01, 2020 · The HOX family genes, also known as type I homeobox genes, contain a conserved sequence consisting of 180–183 base pairs which encodes a homologous domain …

    • Author: Miao Yu, Jun Zhan, Hongquan Zhang
    • Publish Year: 2020
  6. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8890896

    Feb 23, 2022 · To further explore the role of HOX family in HCC patients, we assessed the genetic alterations of the HOX members. We first analyzed the mutation, CNA, and the …

    • DOI: 10.1155/2022/5758601
    • Publication: J Oncol. 2022; 2022: 5758601.
  7. https://en.wikipedia.org/wiki/Hox_gene

    Hox genes, a subset of homeobox genes, are a group of related genes that specify regions of the body plan of an embryo along the head-tail axis of animals. Hox proteins encode and specify the characteristics of 'position', ensuring that the correct structures form in the correct places of the body. For example, Hox genes in insects specify which appendages form on a segment (for example, legs, antennae, and wings in fruit flies), and Hox genes in vertebrates specify the type…

    • Estimated Reading Time: 9 mins
    • https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7695342

      Nov 08, 2020 · In mammals, the HOX family gene contains 39 genes organized into four clusters, called HOXA, HOXB, HOXC, and HOXD, which are located in four different chromosomes …

    • https://www.sciencedirect.com/topics/neuroscience/hox-gene

      In addition to Hox genes, several Hox protein cofactors are expressed in tissues that modify Hox gene specificity. 133 Of high relevance, Hox cofactors Meis1, Meis2, and Pbx1 were recently …

    • https://www.ancestry.com/name-origin?surname=hox

      The Hox family name was found in the USA, the UK, Canada, and Scotland between 1840 and 1920. The most Hox families were found in USA in 1880. In 1840 there were 2 Hox families …

    • https://www.hindawi.com/journals/jo/2022/5758601

      Feb 23, 2022 · To further explore the role of HOX family in HCC patients, we assessed the genetic alterations of the HOX members. We first analyzed the mutation, CNA, and the …

    • https://en.wikipedia.org/wiki/Homeobox

      A homeobox is a DNA sequence, around 180 base pairs long, that regulates large-scale anatomical features in the early stages of embryonic development. For instance, mutations in a homeobox may change large-scale anatomical …



    Results by Google, Bing, Duck, Youtube, HotaVN