acetaminophen wikipedia - EAS
- Paracetamol, also known as acetaminophen, [a] is a medication used to treat fever and mild to moderate pain. Common brand names include Tylenol and Panadol.en.wikipedia.org/wiki/Paracetamol
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Paracetamol, also known as acetaminophen, is a medication used to treat fever and mild to moderate pain. Common brand names include Tylenol and Panadol. At a standard dose, paracetamol only slightly decreases body temperature; it is inferior to ibuprofen in that respect, and the benefits of its use for … 查看更多內容
Fever
Paracetamol is a drug of choice for reducing fever. However, there has been a lack of research on its antipyretic properties, particularly in adults. The most recent review on … 查看更多內容Prokinetic agents such as metoclopramide accelerate gastric emptying, shorten time (tmax) to paracetamol peak blood plasma concentration (Cmax), … 查看更多內容
Synthesis
Classical methods
The classical methods for the production of paracetamol involve the acetylation of 4-aminophenol with acetic anhydride as the last step. They differ in how 4-aminophenol is … 查看更多內容Gastrointestinal adverse effects such as nausea and abdominal pain are common, and their frequency is similar to that of ibuprofen. Increase in risk-taking behavior is possible. … 查看更多內容
Pharmacodynamics
Paracetamol appears to exert its effects through two mechanisms: the inhibition of cyclooxygenase and actions of its metabolite AM404.
Supporting the first mechanism, pharmacologically … 查看更多內容Acetanilide was the first aniline derivative serendipitously found to possess analgesic as well as antipyretic properties, and was quickly introduced into medical practice under the name of 查看更多內容
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