The earliest cities in history were in the ancient Near East, an area covering roughly that of the modern Middle East: its history began in the 4th millennium BC and ended, depending on the interpretation of the term, either with the conquest by the Achaemenid Empire in the 6th century BC or with that by Alexander the Great in the 4th century BC.. The largest cities of the Bronze …

The genetic history of the Middle East is the subject of research within the fields of human population genomics, Archaeogenetics and Middle Eastern studies.Researchers use Y-DNA, mtDNA, and other autosomal DNAs to identify the genetic history of ancient and modern populations of Egypt, Persia, Mesopotamia, Anatolia, Arabia, the Levant, and other areas.