endochondral ossification wikipedia - EAS
- Endochondral ossification is the process by which the embryonic cartilaginous model of most bones contributes to longitudinal growth and is gradually replaced by bone.www.wikipathways.org/index.php/Pathway:WP474
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Endochondral ossification is one of the two essential processes during fetal development of the mammalian skeletal system by which bone tissue is produced. Unlike intramembranous ossification, the other process by which bone tissue is produced, cartilage is present during endochondral … See more
The cartilage model will grow in length by continuous cell division of chondrocytes, which is accompanied by further secretion of extracellular matrix. This is called interstitial growth. The process of appositional growth … See more
About the time of birth in mammals, a secondary ossification center appears in each end (epiphysis) of long bones. Periosteal buds carry mesenchyme and blood vessels in … See more
• Masson Goldner trichrome stain of growth plate in a rabbit tibia.
• Section of fetal bone of cat. ir. Irruption of the subperiosteal tissue. p. Fibrous layer of the periosteum. o. Layer of osteoblasts. im. Subperiosteal bony deposit. (From Quain’s “Anatomy,” … See moreThe first site of ossification occurs in the primary center of ossification, which is in the middle of diaphysis (shaft). Then:
1. Formation of periosteum
2. Formation of bone collar
3. Calcification of matrix See moreThe growth in diameter of bones around the diaphysis occurs by deposition of bone beneath the periosteum. Osteoclasts in the interior cavity continue to resorb bone until its ultimate thickness is achieved, at which point the rate of formation on the outside and degradation … See more
Tubular and flat bones, vertebrae, the skull base, ethmoids, and the ends of the clavicles are formed by endochondral ossification. See more
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