WebGene expression is the process by which information from a gene is used in the synthesis of a functional gene product that enables it to produce end products, protein or non-coding RNA, and ultimately affect a phenotype, as the final effect.These products are often proteins, but in non-protein-coding genes such as transfer RNA (tRNA) and small nuclear RNA …

WebRegulation of gene expression, or gene regulation, includes a wide range of mechanisms that are used by cells to increase or decrease the production of specific gene products (protein or RNA).Sophisticated programs of gene expression are widely observed in biology, for example to trigger developmental pathways, respond to environmental …

WebConflicting definitions of 'gene' There are lots of different ways to use the term "gene." Richard Dawkins, for example, wrote a book called "The Selfish Gene" where 'gene' simply meant any part of the chromosome that was subject to natural selection. This 'gene' is often referred to as the "Mendelian gene" whereas the physical gene described in this article is …

WebNon-viral vectors for gene therapy present certain advantages over viral methods, such as large scale production and low host immunogenicity.However, non-viral methods initially produced lower levels of transfection and gene expression, and thus lower therapeutic efficacy.Newer technologies offer promise of solving these problems, with the advent of …

WebGene expression profiling. Gene expression profiling is a technique used in molecular biology to query the expression of thousands of genes simultaneously. While almost all cells in an organism contain the entire genome of the organism, only a small subset of those genes is expressed as messenger RNA (mRNA) at any given time, and their relative ...

WebAlleles. The ABO gene resides on chromosome 9 at the band 9q34.2 and contains 7 exons. The ABO locus encodes three alleles, that is, 3 variants of the same gene.One allele is derived from each parent. The A allele produces α-1,3-N-acetylgalactosamine transferase (A-transferase), which catalyzes the transfer of GalNAc residues from the UDP-GalNAc …

WebCalcitonin gene-related peptide (CGRP) is a member of the calcitonin family of peptides consisting of calcitonin, amylin, adrenomedullin, adrenomedullin 2 and calcitonin‑receptor‑stimulating peptide.Calcitonin is mainly produced by thyroid C cells whilst CGRP is secreted and stored in the nervous system. This peptide, in humans, exists in …

WebL'expression des gènes, encore appelée expression génique ou expression génétique, désigne l'ensemble des processus biochimiques par lesquels l'information héréditaire stockée dans un gène est lue pour aboutir à la fabrication de molécules qui auront un rôle actif dans le fonctionnement cellulaire, ...

WebFat mass and obesity-associated protein also known as alpha-ketoglutarate-dependent dioxygenase FTO is an enzyme that in humans is encoded by the FTO gene located on chromosome 16.As one homolog in the AlkB family proteins, it is the first mRNA demethylase that has been identified. Certain alleles of the FTO gene appear to be …

WebGene silencing is the regulation of gene expression in a cell to prevent the expression of a certain gene. Gene silencing can occur during either transcription or translation and is often used in research. In particular, methods used to silence genes are being increasingly used to produce therapeutics to combat cancer and other diseases, such as infectious …