glucocorticoid wikipedia - EAS

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  1. Glucocorticoids ( GCs) are steroid hormones made in our adrenal glands. They bind to cell receptors. Glucocorticoids regulate glucose metabolism. GCs are part of the feedback system for the immune system. They do things like reducing inflammation. They stimulate the creation of glucose from non-carbohydrate carbons, such as proteins.
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    What are glucocorticoids and what do they do?

    What glucocorticoids treat

    • Autoimmune disorders. Autoimmune diseases can cause extensive damage from inflammation when the body mistakenly attacks itself.
    • Allergies and asthma. Allergies and asthma are conditions in which your immune system responds to normally harmless substances.
    • Adrenal insufficiency. ...
    • Heart failure. ...
    • Cancer. ...
    • Skin conditions. ...
    • Surgery. ...
    What is the difference between glucocorticoid and mineralocorticoid?
    Glucocorticoids are chiefly produced in the zona fasciculata of the adrenal cortex, whereas mineralocorticoids are synthesized in the zona glomerulosa. Cortisol (or hydrocortisone) is the most important human glucocorticoid.
    www.difference.wiki/glucocorticoids-vs-mineralocorticoids/
    Do glucocorticoids suppress immune system?
    When administered at pharmacological dosages, glucocorticosteroid hormones alter leukocyte kinetics, phagocytic cell function, cell-mediated immunity, and, to a lesser extent, humoral immunity. These properties are used to advantage in the treatment of immunologically mediated disease.
    www.uptodate.com/contents/glucocorticoid-effects-on-th…
    What are some glucocorticoid drugs?

    What Are Glucocorticoid Drugs?

    • Kartizon
    • Prednisone
    • Triamsinolone
    • Budesonide
    • Beklimetazone
    • Betametazon
    • Dexamethasone
    • Hydrocortisone
    • Methylprednisolone
    • Prednisolone
    www.webmd.com/multiple-sclerosis/what-are-glucocortic…
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    See all on Wikipedia
    https://en.wikipedia.org/wiki/Glucocorticoid

    Glucocorticoids (or, less commonly, glucocorticosteroids) are a class of corticosteroids, which are a class of steroid hormones. Glucocorticoids are corticosteroids that bind to the glucocorticoid receptor that is present in almost every vertebrate animal cell. The name "glucocorticoid" is a … See more

    Glucocorticoid effects may be broadly classified into two major categories: immunological and metabolic. In addition, glucocorticoids play important roles in fetal development and body fluid homeostasis.
    Immune See more

    Therapeutic use image
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    A variety of synthetic glucocorticoids, some far more potent than cortisol, have been created for therapeutic use. They differ in both pharmacokinetics (absorption factor, half-life, volume of distribution, clearance) and pharmacodynamics (for example the … See more

    Glucocorticoid drugs currently being used act nonselectively, so in the long run they may impair many healthy anabolic processes. To prevent this, much research has been focused recently on the elaboration of selectively acting glucocorticoid … See more

    • Wolkowitz OM, Burke H, Epel ES, Reus VI (Oct 2009). "Glucocorticoids. Mood, memory, and mechanisms". Annals of the New York Academy of Sciences. 1179: 19–40. See more

    Overview image

    Transactivation
    Glucocorticoids bind to the cytosolic glucocorticoid receptor, a type of nuclear receptor that is activated by ligand binding. After a hormone binds to the corresponding receptor, the newly formed complex See more

    Glucocorticoids may be used in low doses in adrenal insufficiency. In much higher doses, oral or inhaled glucocorticoids are used to suppress various allergic, inflammatory, and autoimmune disorders. Inhaled glucocorticoids are the second-line treatment for See more

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  4. https://simple.wikipedia.org/wiki/Glucocorticoid

    WebGlucocorticoids (GCs) are steroid hormones made in our adrenal glands. They bind to cell receptors. Glucocorticoids regulate glucose metabolism. GCs are part of the …

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    • https://de.wikipedia.org/wiki/Glucocorticoide

      Die Biosynthese der Corticoide startet wie bei allen Steroiden beim Cholesterin, das entweder mit der Nahrung aufgenommen wird oder (in weitaus größerer Menge) aus Mevalonat gebildet wird. Zwischenprodukt ist Pregnenolon, das auf mehreren möglichen Wegen zu Cortisol, und dieses in der Folge zu Cortison, umgesetzt wird. Es gibt einen ausgeprägten Tagesrhythmus mit einem Minimum um Mitternacht und einem Maximum zwischen 6 und 8 Uhr morgens.

      • Estimated Reading Time: 8 mins
      • https://vi.wikipedia.org/wiki/Glucocorticoid

        WebGlucocorticoid là corticosteroid liên kết với thụ thể glucocorticoid. Chúng có mặt ở hầu hết các tế bào động vật có xương sống . Cái tên glucocorticoid ( gluco se + cort ex + ster …

        • Mã ATC: H02AB
        • Đồng nghĩa: Corticosteroid; Glucocorticosteroid
      • https://en.wikipedia.org/wiki/Glucocorticoid_receptor
        Image
        Like the other steroid receptors, the glucocorticoid receptor is modular in structure and contains the following domains (labeled A - F): 1. A/B - N-terminalregulatory domain 2. C - DNA-binding domain(DBD) 3. D- hinge region 4. E- ligand-binding domain (LBD) 5. F - C-terminaldomain
        See more on en.wikipedia.org
        • Aliases: NR3C1, GCCR, GCR, GCRST, GR, …
        • PDB: Ortholog search: PDBe RCSB
      • https://es.wikipedia.org/wiki/Glucocorticoide

        WebLos glucocorticoides son hormonas de la familia de los corticosteroides que participan en la regulación del metabolismo de carbohidratos favoreciendo la

      • https://en.wikipedia.org/wiki/Topical_glucocorticoids

        WebTopical glucocorticoids are used in the treatment of many skin conditions. They provide anti-inflammatory, antimitotic, and immune-system suppressing actions through various …

      • https://en.wikipedia.org/wiki/List_of_corticosteroids

        WebList of corticosteroids - Wikipedia List of corticosteroids Steroid ring system. This is a list of corticosteroids ( glucocorticoids and mineralocorticoids) or derivatives of cortisol ( …

      • https://en.wikipedia.org/wiki/Glucocorticoid_remediable_aldosteronism

        WebGlucocorticoid remediable aldosteronism also describable as aldosterone synthase hyperactivity, is an autosomal dominant disorder in which the increase in aldosterone …

      • https://en.wikipedia.org/wiki/Antiglucocorticoid

        WebIn Wikidata. An antiglucocorticoid is a drug which reduces glucocorticoid activity in the body. They include direct glucocorticoid receptor antagonists such as mifepristone and …

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