glucocorticoid wikipedia - EAS
- Glucocorticoids ( GCs) are steroid hormones made in our adrenal glands. They bind to cell receptors. Glucocorticoids regulate glucose metabolism. GCs are part of the feedback system for the immune system. They do things like reducing inflammation. They stimulate the creation of glucose from non-carbohydrate carbons, such as proteins.simple.wikipedia.org/wiki/Glucocorticoid
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Glucocorticoids (or, less commonly, glucocorticosteroids) are a class of corticosteroids, which are a class of steroid hormones. Glucocorticoids are corticosteroids that bind to the glucocorticoid receptor that is present in almost every vertebrate animal cell. The name "glucocorticoid" is a … See more
Glucocorticoid effects may be broadly classified into two major categories: immunological and metabolic. In addition, glucocorticoids play important roles in fetal development and body fluid homeostasis.
Immune See moreA variety of synthetic glucocorticoids, some far more potent than cortisol, have been created for therapeutic use. They differ in both pharmacokinetics (absorption factor, half-life, volume of distribution, clearance) and pharmacodynamics (for example the … See more
Glucocorticoid drugs currently being used act nonselectively, so in the long run they may impair many healthy anabolic processes. To prevent this, much research has been focused recently on the elaboration of selectively acting glucocorticoid … See more
• Wolkowitz OM, Burke H, Epel ES, Reus VI (Oct 2009). "Glucocorticoids. Mood, memory, and mechanisms". Annals of the New York Academy of Sciences. 1179: 19–40. See more
Transactivation
Glucocorticoids bind to the cytosolic glucocorticoid receptor, a type of nuclear receptor that is activated by ligand binding. After a hormone binds to the corresponding receptor, the newly formed complex See moreGlucocorticoids may be used in low doses in adrenal insufficiency. In much higher doses, oral or inhaled glucocorticoids are used to suppress various allergic, inflammatory, and autoimmune disorders. Inhaled glucocorticoids are the second-line treatment for See more
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