The Human Genome Project was a 15 year-long publicly funded project initiated in 1990 with the objective of determining the DNA sequence of the entire euchromatic human genome within 13 years. 查看更多內容

The sequencing of the human genome holds benefits for many fields, from molecular medicine to human evolution. The Human Genome Project, through its sequencing of … 查看更多內容

In 1998, a similar, privately funded quest was launched by the American researcher Craig Venter, and his firm Celera Genomics. Venter was a scientist at the NIH during the early 1990s when the project was initiated. The $300M Celera effort was … 查看更多內容

With the sequence in hand, the next step was to identify the genetic variants that increase the risk for common diseases like cancer and … 查看更多內容

Notably, the project was not able to sequence all of the DNA found in human cells; rather, the aim was to sequence only euchromatic regions of the nuclear genome, which make up 92.1% of the human genome. The remaining 7.9% exists in scattered 查看更多內容

The process of identifying the boundaries between genes and other features in a raw DNA sequence is called genome annotation and is in the domain of bioinformatics. While expert biologists make the best annotators, their work proceeds … 查看更多內容

In the International Human Genome Sequencing Consortium (IHGSC) public-sector HGP, researchers collected blood (female) or … 查看更多內容