Extended-release (or slow-release) formulations of morphine are those whose effect last substantially longer than bare morphine, availing for e.g. one administration per day. Conversion between extended-release and immediate-release (or "regular") morphine is easier than conversion to or from an equianalgesic dose of another opioid with different half-life, with less …

Chimie. La codéine est un alcaloïde morphinique, présent sous forme de base dans l'opium.. Néanmoins, elle est utilisée en thérapeutique majoritairement sous forme de sels (phosphate notamment). Elle est extrêmement proche de la morphine, dont elle ne diffère que par un groupement méthyle en position 3. On peut d'ailleurs effectuer la synthèse de la morphine à …

Codeine is an opiate and prodrug of morphine used to treat pain, coughing, and diarrhea.It is found naturally in the sap of the opium poppy, Papaver somniferum. It is typically used to treat mild to moderate degrees of pain. Greater benefit may occur when combined with paracetamol (acetaminophen) or a nonsteroidal anti-inflammatory drug (NSAID) such as aspirin or ibuprofen.