nucleotides wikipedia - EAS
- Nucleotides are organic molecules consisting of a nucleoside and a phosphate. They serve as monomeric units of the nucleic acid polymers – deoxyribonucleic acid (DNA) and ribonucleic acid (RNA), both of which are essential biomolecules within all life-forms on Earth.
RNA
Ribonucleic acid (RNA) is a polymeric molecule implicated in various biological roles in coding, decoding, regulation, and expression of genes. RNA and DNA are nucleic acids, and, along with proteins and carbohydrates, constitute the three major macromolecules essential for all known for…
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Nucleotides are organic molecules consisting of a nucleoside and a phosphate. They serve as monomeric units of the nucleic acid polymers – deoxyribonucleic acid (DNA) and ribonucleic acid (RNA), both of which are essential biomolecules within all life-forms on Earth. Nucleotides are obtained in the diet and are … See more
A nucleotide is composed of three distinctive chemical sub-units: a five-carbon sugar molecule, a nucleobase (the two of which together are called a nucleoside), and one phosphate group. With all three … See more
Theories about the origin of life require knowledge of chemical pathways that permit formation of life’s key building blocks under plausible prebiotic conditions. The RNA world hypothesis holds that in the primordial soup there existed free-floating See more
Several nucleotide derivatives have been used as antivirals against hepatitis and HIV. Tenofovir disoproxil, Tenofovir alafenamide and Sofosbuvir are examples of NRTI used against hepatitis. Whereas certain drugs like Mericitabine, Lamivudine, Entecavir and Telbivudine for … See more
The IUPAC has designated the symbols for nucleotides. Apart from the five (A, G, C, T/U) bases, often degenerate bases are used especially for designing PCR primers. These nucleotide codes are listed here. Some primer sequences may also include the character "I", … See more
Nucleotides can be synthesized by a variety of means both in vitro and in vivo.
In vitro, protecting groups may be used during laboratory production of nucleotides. A purified See moreAn unnatural base pair (UBP) is a designed subunit (or nucleobase) of DNA which is created in a laboratory and does not occur in nature. Examples include d5SICS and dNaM. These artificial nucleotides bearing hydrophobic nucleobases, … See more
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