The liver is a reddish-brown, wedge-shaped organ with two lobesof unequal size and shape. A human liver normally weighs approximately 1.5 kg (3.3 lb) and has a width of about 15 cm (6 in). There is considerable size variation

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Organogenesis, the development of the organs, takes place from the third to the eighth week during embryogenesis. The origins of the liver lie in both the ventral portion of the foregut endoderm (endoderm being one of the three embryonic germ layers)

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The various functions of the liver are carried out by the liver cells or hepatocytes. The liver is thought to be responsible for up to 500 separate functions, usually in combination with other systems and organs. Currently, no artificial organor

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Disease
The liver is a vital organ and supports almost every other organ in the body. Because of its strategic location and multidimensional

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Some cultures regard the liver as the seat of the soul. In Greek mythology, the gods punished Prometheusfor revealing fire to humans by chaining him

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The liver is found in all vertebrates and is typically the largest internal organ. Its form varies considerably in different species, and is largely determined by the shape and arrangement of the surrounding organs. Nonetheless, in most species it is divided into right and left lobes;

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• Porphyria
• Johann Joseph Dömling (published Is the liver a purifying organ in 1798)

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