https://www.ncbi.nlm.nih.gov › pmc › articles › PMC7266186
Mar 26, 2020 · Rabies, a zoonotic disease after biting of rabid animals, is the most feared human infections with the highest case fatality rate, approximately 100%. Rabies virus being neurotropic travels retrogradely to diencephalon, hippocampus, and brainstem and causes neuronal dysfunction such as autonomic instability leading to death.