apomorfie wikipedia - EAS

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  2. Apomorphine, sold under the brand name Apokyn among others, is a type of aporphine having activity as a non- selective dopamine agonist which activates both D 2 -like and, to a much lesser extent, D 1 -like receptors. It also acts as an antagonist of 5-HT 2 and α-adrenergic receptors with high affinity.
    Formula: C₁₇H₁₇NO₂
    Metabolism: Liver, phase II
    Pregnancy category: AU: B3
    Trade names: Apokyn, Kynmobi
    en.wikipedia.org/wiki/Apomorphine
    en.wikipedia.org/wiki/Apomorphine
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  3. People also ask
    What is an example of an apomorphy?
    [5] An example of an apomorphy is the presence of erect gait, fur, and mammary glands in mammals but not in other vertebrate animals such as amphibians or reptiles, which have retained their ancestral traits of a sprawling gait and lack of fur. [10]
    en.wikipedia.org/wiki/Apomorphy_and_synapomorphy
    What is Apokyn (apomorphine)?
    Apomorphine (brand names Apokyn, Ixense, Spontane, Uprima) is a type of aporphine having activity as a non-selective dopamine agonist which activates both D2-like and, to a much lesser extent, D1-like receptors.
    en.wikipedia.org/wiki/Apomorphine
    What is the Ki of apomorphine?
    It has a Ki of over 10,000 nM (and thus negligible affinity) for β-adrenergic, H 1, and mACh. Apomorphine has a high clearance rate (3–5 L/kg/hr) and is mainly metabolized and excreted by the liver.
    en.wikipedia.org/wiki/Apomorphine
    What is the history of apomorphine?
    The modern medical history of apomorphine begins with its synthesis by Arppe in 1845 from morphine and sulfuric acid, although it was named sulphomorphide at first. Matthiesen and Wright (1869) used hydrochloric acid instead of sulfuric acid in the process, naming the resulting compound apomorphine.
    en.wikipedia.org/wiki/Apomorphine
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    https://en.wikipedia.org/wiki/Apomorphine

    Apomorphine, sold under the brand name Apokyn among others, is a type of aporphine having activity as a non-selective dopamine agonist which activates both D2-like and, to a much lesser extent, D1-like receptors. It also acts as an antagonist of 5-HT2 and α-adrenergic receptors with high affinity. … See more

    Apomorphine is used in advanced Parkinson's disease intermittent hypomobility ("off" episodes), where a decreased response to an anti-Parkinson drug such as L-DOPA causes muscle stiffness and … See more

    The main and absolute contraindication to using apomorphine is the concurrent use of adrenergic receptor antagonists; combined, they cause a severe drop in blood pressure See more

    Mechanism of action
    Apomorphine's R-enantiomer is an agonist of both D1 and D2 dopamine receptors, with higher activity at … See more

    The pharmacological effects of the naturally-occurring analog aporphine in the blue lotus (Nymphaea caerulea) were known to the … See more

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    Nausea and vomiting are common side effects when first beginning therapy with apomorphine; antiemetics such as trimethobenzamide or domperidone, dopamine … See more

    Properties
    Apomorphine has a catechol structure similar to that of dopamine.
    Synthesis See more

    • Apomorphine has a vital part in Agatha Christie's detective story Sad Cypress.
    • The 1965 Tuli Kupferberg song "Hallucination Horrors" recommends apomorphine at the … See more

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  5. https://nl.wikipedia.org/wiki/Apomorfie

    Een apomorfie is in de cladistiek de eigenschap of het kenmerk waarin een bepaald taxon afwijkt van zijn voorouders. Het gaat dus om een kenmerk dat nieuw geëvolueerd is en dat gebruikt kan worden om het te onderscheiden van de zustergroep. Het woord apomorfie is afgeleid van het Griekse ἀπό (apo), "af" en μορφή (morphè), "vorm".
    Een apomorfie kan als een synapomorfie aangeduid worden, een kenmerk dat eerst bij één soor…

    • Estimated Reading Time: 1 min
    • https://cs.wikipedia.org/wiki/Apomorfie

      Apomorfie neboli odvozený znak je vlastnost organismu nebo skupiny organismů, která se nevyskytovala u jejich předků. Apomorfie je tudíž něco, co vzniklo v průběhu evoluce , je …

      • Estimated Reading Time: 40 secs
      • https://en.wikipedia.org/wiki/Apomorphy_and_synapomorphy

        In phylogenetics, an apomorphy is a novel character or character state that has evolved from its ancestral form. A synapomorphy is an apomorphy shared by two or more taxa and is …

      • https://pl.wikipedia.org/wiki/Apomorfia

        Apomorfia, cecha apomorficzna – cecha zaawansowana, ewolucyjnie nowa, niewystępująca u przodków danej linii ewolucyjnej. Jej przeciwieństwem jest plezjomorfia, czyli cecha …

        • Estimated Reading Time: 3 mins
        • https://it.wikipedia.org/wiki/Apomorfia

          Una apomorfia (dal greco ἀπό, "da", nel senso di modificazione, differenziazione, e μορφή, "forma"), o carattere derivato, è un carattere morfologico nuovo, risultato della modificazione di …

        • https://ro.wikipedia.org/wiki/Apomorfină

          Apomorfina este un medicament antiparkinsonian, fiind utilizat în tratamentul bolii Parkinson. [10] [11] [12] Calea de administrare disponibilă este cea subcutanată. [10] …

        • https://www.wikiwand.com/nl/Apomorfie

          Een apomorfie is in de cladistiek de eigenschap of het kenmerk waarin een bepaald taxon afwijkt van zijn voorouders. Het gaat dus om een kenmerk dat nieuw geëvolueerd is en dat …

        • https://www.wikiwand.com/cs/Apomorfie

          Apomorfie neboli odvozený znak je vlastnost organismu nebo skupiny organismů, která se nevyskytovala u jejich předků. Apomorfie je tudíž něco, co vzniklo v průběhu evoluce, je vlastní …

        • https://hu.wikipedia.org/wiki/Apomorfin

          Az apomorfin ( INN: apomorphine) a morfin származékok közé tartozó dopamin agonista gyógyszermolekula. Nem-szelektív dopamin agonista, de D 2 -szerű receptorokon valamivel …

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